Chse 235         Efosa Asemota Drug report #2         Cytotec/ Misoprosto Therapeutic category mucosal Protective gent         Use/ indicator For the treatment and well-grounded profession of NSAID-induced gastroduodenal ulcers. Also indicated for the treatment of duodenal ulcers caused by peptic ulcer Disease (PUD). Adverse reaction The most ghost gastrointestinal adverse events were profligacy (10.7%), abdominal pain (7.3%), nausea (4.2%), flatulence (3.3%), and dyspepsia (3.2%). The relative relative incidence of diarrhea was 7.8% when the thorough daily dose was 400 & small;g. In patients receiving placebo, the incidence of diarrhea was 3.6%. The events were usually transient and piano to moderate in severity. Contraindication/ drug Possible clinical signs that may indicate an overdose may include: sedation, tremor, fever, convulsions, dyspnea, abdominal pain, diarrhea, palpitations, hypotension or bradycardia. Treatment should be symptomatic and supportive. Children: Safety and effectiveness in patients below the bound off on of 18 have not been established. Known esthesia to prostaglandins, prostaglandin analogues or excipients (microcrystalline and hydroxypropyl methylcellulose, sodium starch glycolate and hydrogenated castor oil). Contraindicated in pregnancy.
initial dosage The recommended adult oral exam dosage for the streak and treatment of NSAID-induced gastroduodenal ulcer is 400 to 800 µg a day in divided doses. NSAIDs should be taken agree to the schedule prescribed by the physician. When appropriate, misoprostol an d NSAIDs atomic number 18 to be taken simul! taneously. Misoprostol should be taken after food. root:www.drugs.com, www.pharmclips.com, hypertext transfer protocol://www.rxmed.com,http://www.rxmed.com/b.main/b2.pharmaceutical/b2.prescribe.html If you want to get a plentiful essay, order it on our website:
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